22.10.2015 - TEDD Annual Meeting 2015

TEDD Quote Jens 

TEDD Annual Meeting 2015 - Moving 3D Cell Cultures from Bench to Practice

In 2010 the co-founders ZHAW and InSphero AG launched the TEDD competence centre with funding from the Gebert-Rüf Foundation (BREF 2010). In the past 5 years the TEDD network has established itself and successfully promoted 3D cell culture activities. Company visits, workshops and symposia with both industrial and academic partners have been organized and several network projects started using the platform. Currently, 8 network projects funded by the Swiss government are running successfully.

Three-dimensional (3D) cell culture technology is one of the fastest growing experimental approaches in the life sciences. The 3D cell culture market was valued at $438.1 million in 2013 and is expected to grow to about $2.2 billion in 2019 (BCC Research Biotechnology Report). The technology has progressed to the extent that cell-based in vitro assays are now being used throughout the drug discovery and development chain. A major challenge, however, is the translation of in vitro assays to the corresponding in vivo outcomes. Physiological relevance is a key parameter to improve the predictive power of cell-based assays, and the more we can reflect tissue architecture, composition and function, the more predicitve in vitro assays will become. For this reason 3D cell culture needs to enter its next phase of development: Technology maturation, optimization of assays, protocols and kits, and compatibility with automated lab equipment. The goal is the implementation of easy-to-handle biomimetic tissue constructs that simulate the in vivo condition in a reproducible and reliable way.

22 October, 2015

Kompetenzentrum TEDD, Institut für Chemie und Biologische Chemie, ZHAW Life Science and Facility Management
Wädenswil, Switzerland

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