Tumor microtissue-based efficacy testing from the experts in 3D
3D InSight™ Custom Tumor Microtissues
Whether you work with common or modified immortalized cell lines, PDX tumor cell lines, or complex co-cultures, we can help build the right tumor model for your study. InSphero scientists have optimized the cell culture conditions that enable reliable production of a 3D tumor microtissues from a variety of cancer cell lines to effectively recapitulate the tumor microenvironment. Our Custom Tumor Microtissue Development Services team can prepare 3D InSight™ tumor models from a single cancer cell type or using more complex co-cultures with fibroblasts (NIH3T3 or NHDF), with or without HUVECs. The following table lists some of the many cancer cell lines that our scientists have used to create 3D tumor models.
Tumor Type Cancer Cell Lines Lung A549, Colo699 Liver HepG2, Huh-7 Colorectal HCT-116, HT-29, DLD-1, LS174T, LoVo Breast MCF-7, T47D, MDA-MB-231, MDA-MB-361 Prostate DU-145, PC-3 Glioblastoma SNB-19, LN-18 Ovarian A2780, HEY Cervical C33-A Kidney A498, 786-O Osteosarcoma SAOS-2, HOS, MG-63
3D InSight™ Oncology Services
Once you've determined the tumor model or models in which you would like to perform testing, simply choose from our menu of standardized oncology services:
- Custom Tumor Microtissue Development
- Efficacy Testing
- Combinatorial Drug Testing
- Tumor Relapse Assay
- Antibody Penetration Assay
We'll take it from there and deliver results quickly and confidentially.